Time-Dependent Effects of L-Tryptophan Administration on Urinary Excretion of L-Tryptophan Metabolites
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چکیده
منابع مشابه
Pathological and immunological effects of ingesting L-tryptophan and 1,1'-ethylidenebis (L-tryptophan) in Lewis rats.
The eosinophilia-myalgia syndrome (EMS) has been associated with ingestion of L-tryptophan (L-TRP) produced by a single manufacturer. Epidemiological data implicated 1,1'-ethylidenebis (L-tryptophan) (EBT) (peak 97 or peak E) as a possible etiologic agent. We showed previously that Lewis rats treated with the L-TRP implicated in EMS develop fasciitis and perimyositis similar to those seen in hu...
متن کاملThe effect of tryptophan load and vitamin B 6 supplementation on urinary excretion of tryptophan metabolites in human male subjects.
I. Urinary excretion of tryptophan metabolites of the kynurenine pathway before and after a loading dose of 2 g of L-tryptophan (both before and during supplementation with vitamin B6) was studied in normal young male subjects and in elderly male subjects with prostatic diseases. 2. The increase in urinary excretion of tryptophan metabolites in the normal male subjects after a loading dose of 2...
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The pathogenesis of morphea and other cutaneous sclerosing disorders remain poorly understood. Although they are considered to be autoimmune disorders, abnormal tryptophan metabolism may be involved. Current therapy is directed to supressing the autoimmune response. Demonstration of a therapeutic response to manipulation of the kynurenine pathway would both support a role for abnormal tryptopha...
متن کاملFate of elevated L-tryptophan in the blood of nephrotic rats with oral L-tryptophan administration in their body.
We examined the changes in serum, liver, kidney, brain, and muscle L-tryptophan (Trp) levels in rats with puromycin aminonucleoside (PAN) nephrosis following oral Trp administration in order to elucidate the fate of elevated Trp in the blood of PAN nephrotic rats with oral Trp administration in their body. Before administration, nephrotic rats had higher liver and kidney Trp contents and lower ...
متن کاملEffect of acetoacetate on urinary excretion of xanthurenic acid and other tryptophan metabolites in rats.
I . An experiment was performed to study the eEect of sodium acetoacetate on urinary excretion of santhurenic acid and other tryptophan metabolites in male albino rats. z. Animals were fed on a nicotinic acid-deficient diet for a period of 3 weeks. The animals were then divided into two groups and, after the basal urinary excretion of the tryptophan metabolites had been estimated, the rats of b...
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ژورنال
عنوان ژورنال: Journal of Nutritional Science and Vitaminology
سال: 2014
ISSN: 0301-4800,1881-7742
DOI: 10.3177/jnsv.60.255